Pharmacotherapy A Pathophysiologic Approach

Focusing on the development of enzyme inhibitors as therapeutic drugs, this book provides an overview of the chemistry of major types of enzymes and their inhibitors. The opening chapters introduce readers to the structure, substrates, kinetics, and mechanisms of enzymes. Subsequent chapters discuss various types of enzyme inhibitors and the principles involved in developing them into effective drugs. The book describes the problems that can be encountered in translating results from the bench to the market place and suggests approaches that circumvent these difficulties. This outstanding text for students in pharmacology and medicinal chemistry is also a valuable professional reference.Smith, H. J. is the author of 'Pharmacotherapy A Pathophysiologic Approach', published 2004 under ISBN 9780415334020 and ISBN 0415334020.