Proteomics Today: Protein Assessment and Biomarkers Using Mass Spectrometry, 2D Electrophoresis,and Microarray Technology

The latest and most effective uses of mass spectrometry, 2D electrophoresis, and microarray technology for protein analysis The first step in analyzing complex biochemical systems involves determining the molecular masses of interacting proteins, peptides, and other components. Proteomics, the study of all proteins expressed by a genome, calls for a powerful tool-mass spectrometry-to identify these proteins. A full understanding of the vital role of mass spectrometry in proteomic research necessitates an illuminating text like Proteomics Today. Over the last several years, new emphasis has been placed on the application of proteomics to perform demanding biomedical and biochemical tasks. Proteomics Today clearly describes the contributions of the latest approaches-separation techniques, modern mass spectrometry, two-dimensional electrophoresis, and microarray technology-in meeting these challenges. The emerging roles of imaging mass spectrometry and protein interaction maps are also addressed. In this single comprehensive source, you will find an invaluable examination of all the newest technologies related to: Instrumentation Current strategies for protein quantification SDS-gel electrophoresis Conventional isoelectric focusing in gel matrices, capillaries, and immobilized pH gradients Two-dimensional maps Proteomics in cancer research A must-have guide for scientists and laboratory technicians who study proteins in the pharmaceutical and biotechnology industries, Proteomics Today includes helpful introductions to chapters, complete references, plus insights into future challenges. More than any other resource, Proteomics Today explains how mass spectrometry and its associated tools can turn today's proteomic research challenges into tomorrow's biomedical opportunities.Pier G. Righetti is the author of 'Proteomics Today: Protein Assessment and Biomarkers Using Mass Spectrometry, 2D Electrophoresis,and Microarray Technology', published 2005 under ISBN 9780471648178 and ISBN 0471648175.