1221586
9780125612852
Are you interested in the relationship between mitochondria and your pet protein? Do you have a protein that you think is targeted to mitochondria? Are you working on a disease that causes or is influenced by respiratory chain dysfunction? Are you interested in the role that mitochondria play in cell death? Have you ever wondered what mitochondrial look like or how they move and divide? Approaches to addressing these and other questions are found in Mitochondria. This is the first Methods in Cell Biology volume to be published on the topic in over a decade, an interval that has witnessed phenomenal advances in the field. Key Features * Modern, proven methods that impact on all aspects of mitochondrial structure, function, and biogenesis * Theoretical basis for all methods; not only how they work, but why they work * Contributions from leaders in the field, including Guiseppi Attardi, Ron Butow, and Walter Neupert Topics Covered Include: * Isolation of mitochondria from commonly used cells and tissues * Assays for mitochondrial activities, including respiration, ATP production, permeability, protein import, and interactions with the cytoskeleton * Biochemical and optical methods for studying protein-protein interactions in mitochondria * Approaches to studying mitochondrial replication, transcription, and translation * Transmitochondrial technologies * Methods in microassay data analysisPon, Liza A. is the author of 'Mitochondria Methods in Cell Biology' with ISBN 9780125612852 and ISBN 0125612850.
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