High-Resolution Nmr Techniques in Organic Chemistry

Preface. Acknowledgements. Introduction.lt;/b> The development of high-resolution NMR. Modern NMR and this book. Applying modern NMR techniques. References. Introducing High-resolution NMR.lt;/b> Nuclear spin and resonance. The vector model and pulse excitation. Time and frequency domains. Spin relaxation. Mechanisms for relaxation. References. Practical Aspects of High-resolution NMR.lt;/b> An overview of the NMR spectrometer. Data acquisition and processing. Preparing the sample. Preparing the spectrometer. Spectrometer calibrations. Spectrometer performance tests. References. One-dimensional Techniques.lt;/b> The single-pulse experiment. Spin decoupling methods. Spectrum editing with spin-echoes. Sensitivity enhancement and spectrum editing. Observing quadrupolar nuclei. References. Correlations through the Chemical Bond I: Homonuclear Shift Correlation.lt;/b> Introducing the second dimension. Correlation spectroscopy (COSY). Practical aspects of 2D NMR. Coherence and coherence transfer. Gradient-selected spectroscopy. Alternative COSY sequences. Total correlation spectroscopy (TOCSY). Correlating dilute spins: INADEQUATE. References. Correlations through the Chemical Bond II: Heteronuclear Shift Correlation.lt;/b> Introduction. Sensitivity. Heteronuclear single-bond correlation spectroscopy. Heteronuclear multiple-bond correlation spectroscopy. Traditional X-detected correlation spectroscopy. References. Separating Shifts and Couplings: J-resolved Spectroscopy.lt;/b> Introduction. Heteronuclear J-resolved spectroscopy. Homonuclear J-resolved spectroscopy. "Indirect" homonuclear J-resolved spectroscopy. References. Correlations through Space: The Nuclear Overhauser Effect.lt;/b> Part I: Theoretical Aspects. Introduction. Definition of the NOE. Steady-state NOEs. Transient NOEs. Rotating-frame NOEs. Part II: Practical Aspects. Measuring steady-state NOEs: NOE difference. Measuring transient NOEs: NOESY. Measuring rotating-frame NOEs: ROESY. Measuring heteronuclear NOEs. Experimental considerations. References. Experimental Methods.lt;/b> Composite pulses. Broadband decoupling and spin-locks. Selective excitation and shaped pulses. Solvent suppression. Recent methods. References. Glossary of Acronyms.lt;/b> Index.Claridge, Timothy D. W. is the author of 'High-Resolution Nmr Techniques in Organic Chemistry', published 2000 under ISBN 9780080427980 and ISBN 0080427987.