828353
9780763722616
In recent years, cutting-edge genomic and molecular techniques have profoundly influenced the direction of brain tumor research and modern clinical practice. Genomic and Molecular Neuro-Oncology, edited by Wei Zhang and Gregory N. Fuller, Is an up-to-date reference that documents these important advances and describes their medical and therapeutic implications. Written for a broad range of researchers and clinicians including oncologists, neurologists, pathologists, neuroscientists, residents, postdoctoral fellows, and others in related fields, this volume contains 18 contributions organized in five sections: Genomic and Genetic Alterations in Gliomas, Molecular Alterations in Gliomas, Genomics and Informatics, Animal Models, and Molecular Therapeutics. Each chapter provides a review of a specific subfield of contemporary molecular neuro-oncology, including recently implemented diagnostic and research applications. This book focuses on the latest genomics, molecular, and informatic approaches to neuro-oncology. The broad range of applications illustrated include the facilitation of clinical diagnosis through molecular and genomics techniques, The identification, confirmation and validation of new tumor markers and novel therapeutic targets, gene discovery and subsequent pathway and biology elucidation, And The emerging molecular approach to brain tumor classification. There is a naturally symbiotic relationship between advances in basic knowledge generated through bench research And The clinical translation and application of that knowledge that forms the foundation for each of the chapters in Genomic and Molecular Neuro-Oncology .Zhang, Wei is the author of 'Genomic and Molecular Neuro-Oncology' with ISBN 9780763722616 and ISBN 0763722618.
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